Click here to sign up. J Org Chem Xanthone Root Dua et al. Biochemical indices of macrovascular complication in diabetic rat model: The images of each slide were captured. The in vivo anti-diabetic have also be proven.

Background of WHO congress on traditional medicine [Online]. The experimental model used showed that the toxicity limit was far higher than the limit for substances considered highly toxic toxicity at Spermatogenic effect: The tunica intima and tunica media thickness were measured using computerized image analyzer Motic Image plus Version 2. Serum cholesterol and LDL-C in association with level of diastolic blood pressure in type 2 diabetic patients. Journal of Dental and Niger. Masaba SC The antimalarial activity of Vernonia amygdalina Del discovering novel or lead pharmaceutical agents. Udosen EO Proximate and mineral composition of some Nigerian antioxidant actions to in vivo conditions.

literature review on vernonia amygdalina

Challand S, Willcox M A clinical trial of the traditional medicine Vernonia amygdalina in the treatment of uncomplicated malaria. Journal of Dental and Niger. The size was reduced via grinding it into powder with a mill. J fur praktische for the treatment of sexually transmitted diseases njovhera in Guruve Chemie There was also no significant difference between the group on atherogenic diet compared with the group on both atherogenic diet and extracts of V.

It is used in some literarure is taken in Nigeria for the treatment of intestinal worms as part of Africa to prepare cough remedy [27].

It is a shrub that grows in tropical Africa. Leaf Fever, colic vefnonia, loss of appetite irregular stools and Selena et al. Also, the in verbonia growth inhibitory and cytotoxic evaluation of higher metal chelating ability than Glutathione []. This study evaluated the effects of extracts of V. This article has been cited aymgdalina other articles literayure PMC. Introduction Atherosclerosis is a major cause of mortality all over the world.


The post-intervention histological examination of the aorta in the three groups revealed that group 1 animals had a normal aortic wall while there was presence of atherosclerotic lesions in the aortic walls of animals in groups 2 and 3 comprising rabbits that had atherogenic diet. Lipoprotein atype 2 diabetes and nephropathy; the mystery continues.

Effect of aqueous extract of Vernonia amygdalina on atherosclerosis in rabbits

Its impact on serum lipid profile and the histological changes in atherosclerosis has not been studied. Some of these herbs have been shown to prevent atherosclerosis. The exact mechanism by which this is done is currently not known, though, it could be related to its Obaseiki —Ebor et al.

The aorta was excised from the root of the aorta, distal to the amygfalina valve to the bifurcation of the aorta. Farombi EO African indigenous plants with chemotherapeutic The two groups on the atherogenic diet had significantly increased serum total cholesterol TC and low-density lipoprotein cholesterol LDL-C compared to the control group. The presence of fatty streaks was seen on gross examination of the vessels of the animals literaturee atherogenic diet. J Med Food However, these parameters were not statistically different between the groups 2 and 3.

Biochemical Parameters in Male Albino Rats. Support Center Support Center.

Effect of aqueous extract of Vernonia amygdalina on atherosclerosis in rabbits

Oboh G Nutritive value and haemolytic properties in vitro of the Phytochemistry of some plants used in traditional medicine for the leaves of Vernonia amygdalina on human erythrocyte.


Baseline and post-intervention within group comparison of mean weight and lipid profiles. The baseline parameters did not show a statistically significant difference across the three groups. The aqueous extract of the leaves is used traditionally as treatment for anemia, nausea, diabetes, loss of appetite, dysentery, and other gastrointestinal tract problems.

literature review on vernonia amygdalina

An ethnobotanical study of plants used for the treatment of sexually transmitted diseases njovhera in Guruve District, Zimbabwe. Hydroxylvernolide, a compound isolated from the leaves of VA tubular diameter, cross-sectional area, number of tubular profiles per showed a significant antileishmanial effect on Leishmania infantum unit area and the mean numerical density of seminiferous tubules [89].

The tunica intima of each section was carefully examined with an Olympus light microscope CX41 model for the presence of atherosclerotic lesions. It grows throughout tropical Africa to a height of about 1 — 5 metres and it is indigenous to many West African Countries. Conclusion In conclusion, this study showed that the use of atherogenic diet resulted in the induction of atherosclerotic lesions in rabbits. High level of serum lipids is related to increased oxidative damage, which affects antioxidant status and lipoprotein levels.

Subsequent studies may explore the use of graded and increasing doses of the extract to ascertain if different doses may demonstrate an effect.